ISODEL® Vitamin E TPGS (Tocophersolan)
Pharmaceutical - Nutritional supplement - Food and beverage
Cosmetic - Personal care & Wound care - Veterinary
Vitamin E TPGS, a water soluble derivative of natural Vitamin E, is a multirole excipient for pharmaceutical drug delivery innovation. Vitamin E TPGS is a non-ionic surfactant used as:
Emulsifier - solubilizer of poorly soluble drugs - absorption enhancer - PgP inhibitor - plasticizer for HME - stabilizer of Amorphous Solid Dispersion (ASD) - antioxidant
Vitamin E TPGS is also used as an efficient source of natural Vitamin E both for therapeutic and nutrition purposes.
Vitamin E TPGS in drug formulation
Regulatory
A National Formulary (NF) monograph is in the United States Pharmacopeia / National Formulary (USP/NF) version USP 40 – NF 35.
Several commercial drugs using Vitamin E TPGS are approved by FDA and EMEA, PMDA.
PMC Isochem’s offer
PMC Isochem his producing under GMP USP/NF compliant ISODEL® Vitamin E TPGS for 10 years. PMC Isochem owns a DMF Type II for the acive ingredient application
PMC Isochem offers a robust supply of ISODEL™ Vitamin E TPGS with manufacturing capacity over two GMP FDA Audited plants.
Packaging 1, 20 and 100 kg
Technical support for storage and handling
Information for quality and pharmaceutical regulatory
For more detailed technical support, please contact us
Reference: Yves Robin, Pharmaceutical Technology - January 2015