Skip to main content

Using Tocophersolan for Drug Delivery

2015 Jan 03

A natural Vitamin E derivative is an innovative excipient - Yves Robin, Pharmaceutical Technology - January 2015


Tocophersolan or d-α-tocopheryl polyethylene glycol succinate (TPGS) was developed 60 years ago as a water-soluble form of vitamin E. Its surfactant properties triggered the interest of drug formulation developers before it steadily moved into the toolbox of pharmaceutical drug-delivery innovators. The author gives an overview of TPGS, including its interesting properties, examples found in the literature, and a brief summary of the regulatory status and marketed formulations.